

| 货号 | ARO-A13110 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
InVivoMAb Anti-Staphylococcus aureus Alpha-toxin/hly Antibody (Iv0192) [Iv0192] (ARO-A13110) is a human monoclonal antibody detecting Alpha-hemolysin, Alpha-HL, Alpha-toxin, hly, hla, Staphylococcus aureus in ELISA, Neutralization. Suitable for Staphylococcus aureus.
Highlights
|
| 种属反应性 | Staphylococcus aureus |
| 应用 | ELISA, Neutralization |
| 宿主 | Human |
| 同种型 | IgG1, kappa |
| 克隆号 | Iv0192 |
| 克隆类型 | Monoclonal |
| 靶标 | Alpha-hemolysin, Alpha-HL, Alpha-toxin, hly, hla, Staphylococcus aureus |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 相关产品 | pH 7.4 Dilution Buffer |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P09616 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Alpha-hemolysin (Alpha-toxin/hly) is a ~35 kDa protein. Alpha-toxin binds to the membrane of eukaryotic cells (particularly red blood cells, RBC) forming pores, resulting in hemolysis, with the release of low-molecular weight molecules leading to eventual osmotic RBC lysis. Human RBCs bind much less alpha-toxin than do rabbit RBCs. Heptamer oligomerization and pore formation is required for lytic activity. 1. Walker, B. et al. (1992) The Journal of biological chemistry 267, 10902-9. PMID: 1587866 2. Wilke, GA. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13473-8. PMID: 20624979 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

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