

| 货号 | ARO-A13138 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
InVivoMAb Anti-HCMV/HHV5 gH/UL75 Antibody (Iv0180) [Iv0180] (ARO-A13138) is a human monoclonal antibody detecting Envelope glycoprotein H, gH, gH, UL75 in ELISA, Neutralization. Suitable for Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5).
Highlights
|
| 种属反应性 | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) |
| 应用 | ELISA, Neutralization |
| 宿主 | Human |
| 同种型 | IgG1, kappa |
| 克隆号 | Iv0180 |
| 克隆类型 | Monoclonal |
| 靶标 | Envelope glycoprotein H, gH, gH, UL75 |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 相关产品 | pH 7.4 Dilution Buffer |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P12824 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 背景 | Envelope glycoprotein H (gH/UL75) is a ~84 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. In human cytomegalovirus, forms two distinct complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA, and in glioblastoma cells by interacting with host EPHA2. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

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