Protein A/G purified from cell culture supernatant. — Ensuring high specificity and minimal background.
Validated for Neutralization — Optimized for consistent performance.
种属反应性
Mouse
应用
Neutralization
宿主
Mouse
同种型
IgG1, kappa
克隆号
Iv0016
克隆类型
Monoclonal
靶标
CD16, CD32, Low affinity immunoglobulin gamma Fc region receptor III, IgG Fc receptor III, Fc-gamma RIII, FcRIII, CD16, Fcgr3, Low affinity immunoglobulin gamma Fc region receptor II, Fc gamma receptor IIB, Fc-gamma RII, Fc-gamma-RIIB, FcRII, IgG Fc receptor II beta, Lymphocyte antigen 17, Ly-17, CD32, Fcgr2, Fcgr2b, Ly-17
Protein A/G purified from cell culture supernatant.
Accession号
P08508, P08101
状态
Liquid
保存溶液
0.01M PBS, pH 7.4.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景
Low affinity immunoglobulin gamma Fc region receptor III (CD16/CD32) is a ~30 kDa protein. Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor which binds to IgG1, IgG2a and IgG2b. Mediates neutrophil activation by IgG complexes redundantly with Fcgr4.
1. Hirano, M. et al. (2007) Nature immunology 8, 762-71. PMID: 17558411
2. Jakus, Z. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 180, 618-29. PMID: 18097064
Note
For research use only. Not suitable for clinical or therapeutic use.
