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Anti-MSN Polyclonal Antibody (ARO-A12776)

概述
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参考文献

概述

货号	ARO-A12776
品牌	ProteoGenix
描述	Anti-MSN Polyclonal Antibody (ARO-A12776) is a rabbit polyclonal antibody detecting Membrane-organizing extension spike protein, MSN, Moesin in ELISA, IHC, WB. Suitable for Human, Mouse, Rat. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications. Multi-Species — Cross-reactive for translational research.
种属反应性	Human, Mouse, Rat
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human MSN (Met1-Met577).
靶标	Membrane-organizing extension spike protein, MSN, Moesin
纯化方式	Purified by antigen affinity column.
Accession号	P26038
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Moesin (MSN) is a ~67 kDa protein. Ezrin-radixin-moesin (ERM) family protein that connects the actin cytoskeleton to the plasma membrane and thereby regulates the structure and function of specific domains of the cell cortex. Tethers actin filaments by oscillating between a resting and an activated state providing transient interactions between moesin and the actin cytoskeleton. Once phosphorylated on its C-terminal threonine, moesin is activated leading to interaction with F-actin and cytoskeletal rearrangement. These rearrangements regulate many cellular processes, including cell shape determination, membrane transport, and signal transduction. The role of moesin is particularly important in immunity acting on both T and B-cells homeostasis and self-tolerance, regulating lymphocyte egress from lymphoid organs. 1. Huang, L. et al. (1999) The Journal of biological chemistry 274, 12803-10. PMID: 10212266 2. Urzainqui, A. et al. (2002) Immunity 17, 401-12. PMID: 12387735 3. Iontcheva, I. et al. (2004) Infection and immunity 72, 2312-20. PMID: 15039356 4. Serrador, JM. et al. (1997) The Journal of cell biology 138, 1409-23. PMID: 9298994 5. Serrador, JM. et al. (1998) Blood 91, 4632-44. PMID: 9616160 6. Lagresle-Peyrou, C. et al. (2016) The Journal of allergy and clinical immunology 138, 1681-1689.e8. PMID: 27405666
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

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体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

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V₂ (终体积)

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Anti-MSN Polyclonal Antibody

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