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Anti-Bordetella pertussis ptxA/PTXS1 Polyclonal Antibody (ARO-A13459)

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概述
货号ARO-A13459
品牌ProteoGenix
描述
Anti-Bordetella pertussis ptxA/PTXS1 Polyclonal Antibody (ARO-A13459) is a rabbit polyclonal antibody detecting Pertussis toxin subunit 1, PTX S1, Islet-activating protein S1, IAP S1, NAD-dependent ADP-ribosyltransferase, 2.4.2.-, ptxA, BP3783 in ELISA, IHC, WB. Suitable for Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251).
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Bordetella pertussis ptxA/PTXS (Asp35-Phe269).
靶标Pertussis toxin subunit 1, PTX S1, Islet-activating protein S1, IAP S1, NAD-dependent ADP-ribosyltransferase, 2.4.2.-, ptxA, BP3783
纯化方式Purified by antigen affinity column.
Accession号P04977
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Pertussis toxin subunit 1 (ptxA/PTXS1) is a ~29 kDa protein. S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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