

| 货号 | JN968016 |
|---|---|
| 品牌 | abinScience |
| 描述 |
SYN-005-1B7 (JN968016) is a research-grade recombinant antibody targeting ptxAPTXS1. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 种属反应性 | Bordetella pertussis |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG1-kappa |
| 表达系统 | Mammalian cells |
| 克隆类型 | Monoclonal |
| 靶标 | ptxAPTXS1 |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P04977 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | hu1B7, SYN-005, SYN-005-1B7 |
| 背景 | Pertussis toxin subunit 1 (ptxAPTXS1) is a ~29 kDa protein. S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade SYN-005-1B7



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