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Anti-Mouse RTN4R Polyclonal Antibody (ARO-A11032)

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概述
货号ARO-A11032
品牌ProteoGenix
描述
Anti-Mouse RTN4R Polyclonal Antibody (ARO-A11032) is a rabbit polyclonal antibody detecting Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor) (Nogo66 receptor-1) (NgR1) in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Mouse RTN4R (Thr25-Gly308).
靶标Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor) (Nogo66 receptor-1) (NgR1)
纯化方式Purified by antigen affinity column.
Accession号Q99PI8
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Reticulon-4 receptor (RTN4R/NgR1) is a ~50 kDa protein. Receptor for RTN4, OMG and MAG. Functions as a receptor for the sialylated gangliosides GT1b and GM1. Besides, functions as a receptor for chondroitin sulfate proteoglycans. Can also bind heparin. Intracellular signaling cascades are triggered via the coreceptor NGFR.

1. Fournier, AE. et al. (2001) Nature 409, 341-6. PMID: 11201742
2. Liu, BP. et al. (2002) Science (New York, N.Y.) 297, 1190-3. PMID: 12089450
3. Kim, JE. et al. (2004) Neuron 44, 439-51. PMID: 15504325
4. Williams, G. et al. (2008) The Journal of biological chemistry 283, 16641-52. PMID: 18411262
5. Nakaya, N. et al. (2012) The Journal of biological chemistry 287, 37171-84. PMID: 22923615
6. Dickendesher, TL. et al. (2012) Nature neuroscience 15, 703-12. PMID: 22406547
7. Wills, ZP. et al. (2012) Neuron 73, 466-81. PMID: 22325200
9. Palandri, A. et al. (2015) Cell death & disease 6, e1876. PMID: 26335717
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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