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Mouse RTN4R/NgR1/Nogor Recombinant Protein (C-Fc) (MP096021)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号MP096021
品牌abinScience
描述
Recombinant Mouse RTN4R/NgR1/Nogor Protein, C-Fc (MP096021) expressed in Mammalian Cells, spanning Cys27-Ser447. Purity: >90% by SDS-PAGE.
Highlights
  • Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • Mammalian Expression — Proper folding and native glycosylation.
  • High Purity — >90% purity verified by SDS-PAGE.
表达系统Mammalian cells
Accession号Q99PI8
蛋白长度Cys27-Ser447
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Mus musculus (Mouse)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量73.90 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名NOGOR, NgR, Nogo receptor, Nogo-66 receptor, RTN4R, Reticulon-4 receptor
背景

Reticulon-4 receptor is a ~50 kDa protein. Receptor for RTN4, OMG and MAG. Functions as a receptor for the sialylated gangliosides GT1b and GM1. Besides, functions as a receptor for chondroitin sulfate proteoglycans. Can also bind heparin. Intracellular signaling cascades are triggered via the coreceptor NGFR.

1. Fournier, AE. et al. (2001) Nature 409, 341-6. PMID: 11201742
2. Liu, BP. et al. (2002) Science (New York, N.Y.) 297, 1190-3. PMID: 12089450
3. Kim, JE. et al. (2004) Neuron 44, 439-51. PMID: 15504325
4. Williams, G. et al. (2008) The Journal of biological chemistry 283, 16641-52. PMID: 18411262
5. Nakaya, N. et al. (2012) The Journal of biological chemistry 287, 37171-84. PMID: 22923615
6. Dickendesher, TL. et al. (2012) Nature neuroscience 15, 703-12. PMID: 22406547
7. Wills, ZP. et al. (2012) Neuron 73, 466-81. PMID: 22325200
9. Palandri, A. et al. (2015) Cell death & disease 6, e1876. PMID: 26335717
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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