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Anti-Human TMEM70 Polyclonal Antibody (ARO-A11192)

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概述
货号ARO-A11192
品牌ProteoGenix
描述
Anti-Human TMEM70 Polyclonal Antibody (ARO-A11192) is a rabbit polyclonal antibody detecting TMEM70, Transmembrane protein 70, mitochondrial in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human TMEM70 (Thr163-Lys260).
靶标TMEM70, Transmembrane protein 70, mitochondrial
纯化方式Purified by antigen affinity column.
Accession号Q9BUB7
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Transmembrane protein 70, mitochondrial (TMEM70) is a ~28 kDa protein. Scaffold protein that participates in the c-ring assembly of mitochondrial ATP synthase (F(1)F(0) ATP synthase or complex V) by facilitating the membrane insertion and oligomer formation of the subunit c/ATP5MC1 through its interaction. Therefore, participates in the early stage of mitochondrial ATP synthase biogenesis and also protects subunit c/ATP5MC1 against intramitochondrial proteolysis. In addition, binds the mitochondrial proton-transporting ATP synthase complexes I and may play a role in the stability of its membrane-bound subassemblies.

1. Kovalčíkova, J. et al. (2019) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 33, 14103-14117. PMID: 31652072
2. Sánchez-Caballero, L. et al. (2020) Biochimica et biophysica acta. Bioenergetics 1861, 148202. PMID: 32275929
3. Bahri, H. et al. (2021) Biochimica et biophysica acta. Molecular cell research 1868, 118942. PMID: 33359711
4. Carroll, J. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 33753518
5. Cízková, A. et al. (2008) Nature genetics 40, 1288-90. PMID: 18953340
6. Hejzlarová, K. et al. (2011) Biochimica et biophysica acta 1807, 144-9. PMID: 20937241
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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