

| 货号 | ARO-A11123 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human YEATS2 Polyclonal Antibody (ARO-A11123) is a rabbit polyclonal antibody detecting YEATS2, KIAA1197, YEATS domain-containing protein 2 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human YEATS2 (Asp196-Gly335). |
| 靶标 | YEATS2, KIAA1197, YEATS domain-containing protein 2 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9ULM3 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | YEATS domain-containing protein 2 (YEATS2) is a ~150 kDa protein. Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. 1. Wang, YL. et al. (2008) The Journal of biological chemistry 283, 33808-15. PMID: 18838386 2. Guelman, S. et al. (2009) Molecular and cellular biology 29, 1176-88. PMID: 19103755 3. Zhao, D. et al. (2016) Cell research 26, 629-32. PMID: 27103431 |
| Note | For research use only. |

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