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Anti-Human YEATS2 Polyclonal Antibody (ARO-A11123)

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概述
货号ARO-A11123
品牌ProteoGenix
描述
Anti-Human YEATS2 Polyclonal Antibody (ARO-A11123) is a rabbit polyclonal antibody detecting YEATS2, KIAA1197, YEATS domain-containing protein 2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human YEATS2 (Asp196-Gly335).
靶标YEATS2, KIAA1197, YEATS domain-containing protein 2
纯化方式Purified by antigen affinity column.
Accession号Q9ULM3
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

YEATS domain-containing protein 2 (YEATS2) is a ~150 kDa protein. Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.

1. Wang, YL. et al. (2008) The Journal of biological chemistry 283, 33808-15. PMID: 18838386
2. Guelman, S. et al. (2009) Molecular and cellular biology 29, 1176-88. PMID: 19103755
3. Zhao, D. et al. (2016) Cell research 26, 629-32. PMID: 27103431
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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