首页 > 产品中心 > 抗体 > 一抗

Anti-Human DUT Polyclonal Antibody (ARO-A11309)

价格:
规格:
数量:
  • 概述

  • 图片

  • 参考文献

概述
货号ARO-A11309
品牌ProteoGenix
描述
Anti-Human DUT Polyclonal Antibody (ARO-A11309) is a rabbit polyclonal antibody detecting dUTP pyrophosphatase, DUT, dUTPase, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human DUT (Met112-Asn252).
靶标dUTP pyrophosphatase, DUT, dUTPase, Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
纯化方式Purified by antigen affinity column.
Accession号P33316
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT) is a ~26 kDa protein. Catalyzes the cleavage of 2'-deoxyuridine 5'-triphosphate (dUTP) into 2'-deoxyuridine 5'-monophosphate (dUMP) and inorganic pyrophosphate and through its action efficiently prevents uracil misincorporation into DNA and at the same time provides dUMP, the substrate for de novo thymidylate biosynthesis. Inhibits peroxisome proliferator-activated receptor (PPAR) activity by binding of its N-terminal to PPAR, preventing the latter's dimerization with retinoid X receptor. Essential for embryonic development.

1. Varga, B. et al. (2007) FEBS letters 581, 4783-8. PMID: 17880943
2. Ladner, RD. et al. (1996) The Journal of biological chemistry 271, 7745-51. PMID: 8631816
3. Mol, CD. et al. (1996) Structure (London, England : 1993) 4, 1077-92. PMID: 8805593
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐