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Anti-ALDH7A1 Polyclonal Antibody (ARO-A11663)

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概述
货号ARO-A11663
品牌ProteoGenix
描述
Anti-ALDH7A1 Polyclonal Antibody (ARO-A11663) is a rabbit polyclonal antibody detecting ALDH7A1, Delta1-piperideine-6-carboxylate dehydrogenase, Antiquitin-1, P6c dehydrogenase, Alpha-AASA dehydrogenase, Alpha-aminoadipic semialdehyde dehydrogenase, Aldehyde dehydrogenase family 7 member A1, Betaine aldehyde dehydrogenase, ATQ1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ALDH7A1 (Met1-Gln539).
靶标ALDH7A1, Delta1-piperideine-6-carboxylate dehydrogenase, Antiquitin-1, P6c dehydrogenase, Alpha-AASA dehydrogenase, Alpha-aminoadipic semialdehyde dehydrogenase, Aldehyde dehydrogenase family 7 member A1, Betaine aldehyde dehydrogenase, ATQ1
纯化方式Purified by antigen affinity column.
Accession号P49419
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) is a ~58 kDa protein. Aldehyde dehydrogenase enzyme that mediates important protective effects. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in cellular defense against hyperosmotic stress by metabolizing betaine aldehyde to betaine, an important cellular osmolyte and methyl donor.

1. Mills, PB. et al. (2006) Nature medicine 12, 307-9. PMID: 16491085
2. Brocker, C. et al. (2010) The Journal of biological chemistry 285, 18452-63. PMID: 20207735
3. Mills, PB. et al. (2010) Brain : a journal of neurology 133, 2148-59. PMID: 20554659
4. Brocker, C. et al. (2011) Chemico-biological interactions 191, 269-77. PMID: 21338592
5. Luo, M. et al. (2015) ACS chemical biology 10, 693-7. PMID: 25554827
6. Laciak, AR. et al. (2020) The FEBS journal 287, 173-189. PMID: 31302938
7. Laciak, AR. et al. (2020) Journal of inherited metabolic disease 43, 635-644. PMID: 31652343
8. Korasick, DA. et al. (2024) Chemico-biological interactions 394, 110993. PMID: 38604394
9. Yang, JS. et al. (2025) Cell 188, 2569-2585.e20. PMID: 40233740
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-ALDH7A1 Polyclonal Antibody

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