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Anti-CBR3 Polyclonal Antibody (ARO-A11730)

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概述
货号ARO-A11730
品牌ProteoGenix
描述
Anti-CBR3 Polyclonal Antibody (ARO-A11730) is a rabbit polyclonal antibody detecting Carbonyl reductase [NADPH] 3, Short chain dehydrogenase/reductase family 21C member 2, NADPH-dependent carbonyl reductase 3, CBR3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CBR3 (Met1-Trp277).
靶标Carbonyl reductase [NADPH] 3, Short chain dehydrogenase/reductase family 21C member 2, NADPH-dependent carbonyl reductase 3, CBR3
纯化方式Purified by antigen affinity column.
Accession号O75828
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Carbonyl reductase [NADPH] 3 (CBR3) is a ~30 kDa protein. Catalyzes the NADPH-dependent reduction of carbonyl compounds to their corresponding alcohols. Has low NADPH-dependent oxidoreductase activity. Acts on several orthoquinones, acts as well on non-quinone compounds, such as isatin or on the anticancer drug oracin. Best substrates for CBR3 is 1,2- naphthoquinone, hence could play a role in protection against cytotoxicity of exogenous quinones. Exerts activity toward ortho-quinones but not paraquinones.

1. Miura, T. et al. (2008) Molecular and cellular biochemistry 315, 113-21. PMID: 18493841
2. Lakhman, SS. et al. (2005) Drug metabolism and disposition: the biological fate of chemicals 33, 254-7. PMID: 15537833
3. Pilka, ES. et al. (2009) PloS one 4, e7113. PMID: 19841672
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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