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Anti-Human DDA1 Polyclonal Antibody (ARO-A11896)

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概述
货号ARO-A11896
品牌ProteoGenix
描述
Anti-Human DDA1 Polyclonal Antibody (ARO-A11896) is a rabbit polyclonal antibody detecting Placenta cross-immune reaction antigen 1, PCIA1, PCIA-1, C19orf58, DDA1, DET1- and DDB1-associated protein 1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human DDA1 (Ala2-Thr102).
靶标Placenta cross-immune reaction antigen 1, PCIA1, PCIA-1, C19orf58, DDA1, DET1- and DDB1-associated protein 1
纯化方式Purified by antigen affinity column.
Accession号Q9BW61
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

DET1- and DDB1-associated protein 1 (DDA1) is a ~11 kDa protein. Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex.

1. Pick, E. et al. (2007) Molecular and cellular biology 27, 4708-19. PMID: 17452440
2. Han, T. et al. (2017) Science (New York, N.Y.) 356. PMID: 28302793
3. Uehara, T. et al. (2017) Nature chemical biology 13, 675-680. PMID: 28437394
4. Faust, TB. et al. (2020) Nature chemical biology 16, 7-14. PMID: 31686031
5. Bussiere, DE. et al. (2020) Nature chemical biology 16, 15-23. PMID: 31819272
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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