

| 货号 | HP866022 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human DDA1 Protein, N-GST & C-His (HP866022) expressed in E. coli, spanning Ala2-Thr102. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q9BW61 |
| 蛋白长度 | Ala2-Thr102 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 39.89 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | C19orf58, DDA1, DET1- and DDB1-associated protein 1, PCIA-1, PCIA1, Placenta cross-immune reaction antigen 1 |
| 背景 | DET1- and DDB1-associated protein 1 is a ~11 kDa protein. Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex. 1. Pick, E. et al. (2007) Molecular and cellular biology 27, 4708-19. PMID: 17452440 2. Han, T. et al. (2017) Science (New York, N.Y.) 356. PMID: 28302793 3. Uehara, T. et al. (2017) Nature chemical biology 13, 675-680. PMID: 28437394 4. Faust, TB. et al. (2020) Nature chemical biology 16, 7-14. PMID: 31686031 5. Bussiere, DE. et al. (2020) Nature chemical biology 16, 15-23. PMID: 31819272 |
| Note | For research use only |

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