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Anti-Human DDX3X Polyclonal Antibody (ARO-A12010)

概述
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参考文献

概述

货号	ARO-A12010
品牌	ProteoGenix
描述	Anti-Human DDX3X Polyclonal Antibody (ARO-A12010) is a rabbit polyclonal antibody detecting DEAD box, X isoform, CAP-Rf, DDX3, HLP2, DEAD box protein 3, X-chromosomal, DDX3X, ATP-dependent RNA helicase DDX3X, Helicase-like protein 2, DBX in ELISA, IHC, WB. Suitable for Human. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human DDX3X (Glu161-Ser410).
靶标	DEAD box, X isoform, CAP-Rf, DDX3, HLP2, DEAD box protein 3, X-chromosomal, DDX3X, ATP-dependent RNA helicase DDX3X, Helicase-like protein 2, DBX
纯化方式	Purified by antigen affinity column.
Accession号	O00571
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	ATP-dependent RNA helicase DDX3X is a ~73 kDa protein. Multifunctional ATP-dependent RNA helicase. The ATPase activity can be stimulated by various ribo-and deoxynucleic acids indicative for a relaxed substrate specificity. In vitro can unwind partially double-stranded DNA with a preference for 5'-single-stranded DNA overhangs. Binds RNA G-quadruplex (rG4s) structures, including those located in the 5'-UTR of NRAS mRNA. Involved in many cellular processes, which do not necessarily require its ATPase/helicase catalytic activities (Probable). 1. Franca, R. et al. (2007) Proteins 67, 1128-37. PMID: 17357160 2. Garbelli, A. et al. (2011) PloS one 6, e19810. PMID: 21589879 3. Heaton, SM. et al. (2019) Cells 8. PMID: 31575075 4. Dolde, C. et al. (2018) Journal of cell science 131. PMID: 29222110 5. Herdy, B. et al. (2018) Nucleic acids research 46, 11592-11604. PMID: 30256975 6. Chao, CH. et al. (2006) Cancer research 66, 6579-88. PMID: 16818630 7. Botlagunta, M. et al. (2008) Oncogene 27, 3912-22. PMID: 18264132
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human DDX3X Polyclonal Antibody

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