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Anti-Human SH3PXD2A Polyclonal Antibody (ARO-A12345)

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概述
货号ARO-A12345
品牌ProteoGenix
描述
Anti-Human SH3PXD2A Polyclonal Antibody (ARO-A12345) is a rabbit polyclonal antibody detecting KIAA0418, Tyrosine kinase substrate with five SH3 domains, TKS5, SH3 multiple domains protein 1, SH3PXD2A, SH3MD1, SH3 and PX domain-containing protein 2A, Five SH3 domain-containing protein, Adapter protein TKS5, FISH in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human SH3PXD2A (Met1-Asn129).
靶标KIAA0418, Tyrosine kinase substrate with five SH3 domains, TKS5, SH3 multiple domains protein 1, SH3PXD2A, SH3MD1, SH3 and PX domain-containing protein 2A, Five SH3 domain-containing protein, Adapter protein TKS5, FISH
纯化方式Purified by antigen affinity column.
Accession号Q5TCZ1
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

SH3 and PX domain-containing protein 2A (SH3PXD2A) is a ~125 kDa protein. Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.

1. Jacob, A. et al. (2016) Journal of cell science 129, 4341-4353. PMID: 27789576
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human SH3PXD2A Polyclonal Antibody

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