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Anti-Human YWHAE Polyclonal Antibody (ARO-A12441)

概述
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概述

货号	ARO-A12441
品牌	ProteoGenix
描述	Anti-Human YWHAE Polyclonal Antibody (ARO-A12441) is a rabbit polyclonal antibody detecting 14-3-3E, YWHAE, 14-3-3 protein epsilon in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bos taurus, Chicken, Ovis aries. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications. Multi-Species — Cross-reactive for translational research.
种属反应性	Human, Mouse, Rat, Bos taurus, Chicken, Ovis aries
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human YWHAE (Met1-Gln255).
靶标	14-3-3E, YWHAE, 14-3-3 protein epsilon
纯化方式	Purified by antigen affinity column.
Accession号	P62258
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	14-3-3 protein epsilon (YWHAE) is a ~29 kDa protein. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm. Plays a positive role in the antiviral signaling pathway upstream of TBK1 via interaction with RIGI. 1. Okamoto, Y. et al. (2011) The Journal of biological chemistry 286, 7171-81. PMID: 21189250 2. Zhang, ZD. et al. (2022) Advanced science (Weinheim, Baden-Wurttemberg, Germany) 9, e2105391. PMID: 35343654 3. Wang, X. et al. (2003) Molecular and cellular biology 23, 6013-26. PMID: 12917326 4. Andrews, DDT. et al. (2023) Journal of virology 97, e0060423. PMID: 37555661 5. Liu, HM. et al. (2012) Cell host & microbe 11, 528-37. PMID: 22607805 6. Guo, M. et al. (2023) Cancer biology & therapy 24, 2246203. PMID: 37599448
Note	For research use only.

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公式

C₁ × V₁ = C₂ × V₂

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母液

C₁ (起始浓度)

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V₁ (起始体积)

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工作液

C₂ (终浓度)

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V₂ (终体积)

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Anti-Human YWHAE Polyclonal Antibody

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