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Anti-Human CHCHD3 Polyclonal Antibody (ARO-A12513)

概述
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参考文献

概述

货号	ARO-A12513
品牌	ProteoGenix
描述	Anti-Human CHCHD3 Polyclonal Antibody (ARO-A12513) is a rabbit polyclonal antibody detecting MICOS complex subunit MIC19, Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, MINOS3, MIC19, CHCHD3 in ELISA, IHC, WB. Suitable for Human, Mouse, Bos taurus. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications. Multi-Species — Cross-reactive for translational research.
种属反应性	Human, Mouse, Bos taurus
应用	ELISA, IHC, WB
宿主	Rabbit
克隆类型	Polyclonal
同种型	IgG
免疫原	E. coli - derived recombinant Human CHCHD3 (Ser58-Gly227).
靶标	MICOS complex subunit MIC19, Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, MINOS3, MIC19, CHCHD3
纯化方式	Purified by antigen affinity column.
Accession号	Q9NX63
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	MICOS complex subunit MIC19 (CHCHD3) is a ~26 kDa protein. Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. 1. Ott, C. et al. (2015) PloS one 10, e0120213. PMID: 25781180 2. Stephan, T. et al. (2020) The EMBO journal 39, e104105. PMID: 32567732 3. Hu, C. et al. (2020) Cell death & disease 11, 940. PMID: 33130824 4. Liu, H. et al. (2012) PloS one 7, e34832. PMID: 22567091
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-Human CHCHD3 Polyclonal Antibody

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