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Anti-Human DDX1 Polyclonal Antibody (ARO-A12484)

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概述
货号ARO-A12484
品牌ProteoGenix
描述
Anti-Human DDX1 Polyclonal Antibody (ARO-A12484) is a rabbit polyclonal antibody detecting DEAD box protein retinoblastoma, ATP-dependent RNA helicase DDX1, DEAD box protein 1, DBP-RB, DDX1 in ELISA, IHC, WB. Suitable for Mouse, Bos taurus, Chicken, Human, Macaca fascicularis, Pongo abelii, Rat, Xenopus laevis.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Mouse, Bos taurus, Chicken, Human, Macaca fascicularis, Pongo abelii, Rat, Xenopus laevis
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human DDX1 (Gln72-Leu283).
靶标DEAD box protein retinoblastoma, ATP-dependent RNA helicase DDX1, DEAD box protein 1, DBP-RB, DDX1
纯化方式Purified by antigen affinity column.
Accession号Q92499
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

ATP-dependent RNA helicase DDX1 is a ~82 kDa protein. Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. Possesses ATPase activity on various RNA, but not DNA polynucleotides. May play a role in RNA clearance at DNA double-strand breaks (DSBs), thereby facilitating the template-guided repair of transcriptionally active regions of the genome. Together with RELA, acts as a coactivator to enhance NF-kappa-B-mediated transcriptional activation.

1. Popow, J. et al. (2014) Nature 511, 104-7. PMID: 24870230
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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