Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景
Non-POU domain-containing octamer-binding protein (NONO) is a ~54 kDa protein. DNA- and RNA binding protein, involved in several nuclear processes. Binds the conventional octamer sequence in double-stranded DNA. Also binds single-stranded DNA and RNA at a site independent of the duplex site. Involved in pre-mRNA splicing, probably as a heterodimer with SFPQ. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b.
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3. Mircsof, D. et al. (2015) Nature neuroscience 18, 1731-6. PMID: 26571461
8. Morchikh, M. et al. (2017) Molecular cell 67, 387-399.e5. PMID: 28712728
