Anti-Human NONO Reference Antibody (PAT-LM1, RUO) (HS752016)

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概述

货号	HS752016
品牌	abinScience
描述	Anti-Human NONO (PAT-LM1) (HS752016) is a research-grade recombinant antibody targeting 54 kDa nuclear RNA- and DNA-binding protein. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG
克隆号	PAT-LM1
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	54 kDa nuclear RNA- and DNA-binding protein, NRB54, p54nrb, NMT55, NonO protein, p54(nrb), 55 kDa nuclear protein, NONO, DNA-binding p52/p100 complex, 52 kDa subunit, Non-POU domain-containing octamer-binding protein
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q15233
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	PAT-LM1, PATLM1, PATLM1
背景	Non-POU domain-containing octamer-binding protein (NONO) is a ~54 kDa protein. DNA- and RNA binding protein, involved in several nuclear processes. Binds the conventional octamer sequence in double-stranded DNA. Also binds single-stranded DNA and RNA at a site independent of the duplex site. Involved in pre-mRNA splicing, probably as a heterodimer with SFPQ. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. 1. Zhang, Z. et al. (2001) Cell 106, 465-75. PMID: 11525732 2. Peng, R. et al. (2002) RNA (New York, N.Y.) 8, 1334-47. PMID: 12403470 3. Mircsof, D. et al. (2015) Nature neuroscience 18, 1731-6. PMID: 26571461 8. Morchikh, M. et al. (2017) Molecular cell 67, 387-399.e5. PMID: 28712728
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human NONO (PAT-LM1)

参考文献

产品说明书

Anti-Human NONO Reference Antibody (PAT-LM1, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NONO Reference Antibody (PAT-LM1, RUO) (HS752016)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NONO Reference Antibody (PAT-LM1, RUO) (HS752016)

概述

图片

参考文献

产品说明书

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