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Anti-Human IFT20 Polyclonal Antibody (ARO-A12644)

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概述
货号ARO-A12644
品牌ProteoGenix
描述
Anti-Human IFT20 Polyclonal Antibody (ARO-A12644) is a rabbit polyclonal antibody detecting hIFT20, IFT20, Intraflagellar transport protein 20 homolog in ELISA, IHC, WB. Suitable for Human, Mouse, Bos taurus, Danio rerio, Xenopus laevis, Xenopus tropicalis.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Bos taurus, Danio rerio, Xenopus laevis, Xenopus tropicalis
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human IFT20 (Met1-Lys132).
靶标hIFT20, IFT20, Intraflagellar transport protein 20 homolog
纯化方式Purified by antigen affinity column.
Accession号Q8IY31
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Intraflagellar transport protein 20 homolog (IFT20) is a ~15 kDa protein. Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Required for protein stability of E3 ubiquitin ligases CBL and CBLB that mediate ubiquitination and internalization of PDGFRA for proper feedback inhibition of PDGFRA signaling. Essential for male fertility.

1. Pugacheva, EN. et al. (2007) Cell 129, 1351-63. PMID: 17604723
2. Follit, JA. et al. (2006) Molecular biology of the cell 17, 3781-92. PMID: 16775004
3. Schmid, FM. et al. (2018) The Journal of cell biology 217, 151-161. PMID: 29237719
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human IFT20 Polyclonal Antibody

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