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Anti-FIS1 Polyclonal Antibody (ARO-A13578)

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概述
货号ARO-A13578
品牌ProteoGenix
描述
Anti-FIS1 Polyclonal Antibody (ARO-A13578) is a rabbit polyclonal antibody detecting Mitochondrial fission 1 protein, FIS1 homolog, Tetratricopeptide repeat protein 11, FIS1, TTC11, hFis1, TPR repeat protein 11 in ELISA, IHC, WB. Suitable for Mouse, Bos taurus, Human, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Mouse, Bos taurus, Human, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human FIS1 (Met1-Ala117).
靶标Mitochondrial fission 1 protein, FIS1 homolog, Tetratricopeptide repeat protein 11, FIS1, TTC11, hFis1, TPR repeat protein 11
纯化方式Purified by antigen affinity column.
Accession号Q9Y3D6
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Mitochondrial fission 1 protein (FIS1) is a ~16 kDa protein. Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. May not be essential for the assembly of functional fission complexes and the subsequent membrane scission event. Also mediates peroxisomal fission. May act when the products of fission are directed toward mitochondrial homeostasis, mitophagy, or apoptosis.

1. James, DI. et al. (2003) The Journal of biological chemistry 278, 36373-9. PMID: 12783892
2. Yoon, Y. et al. (2003) Molecular and cellular biology 23, 5409-20. PMID: 12861026
3. Stojanovski, D. et al. (2004) Journal of cell science 117, 1201-10. PMID: 14996942
4. Losón, OC. et al. (2013) Molecular biology of the cell 24, 659-67. PMID: 23283981
5. Yu, T. et al. (2005) Journal of cell science 118, 4141-51. PMID: 16118244
6. Koirala, S. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, E1342-51. PMID: 23530241
7. Shen, Q. et al. (2014) Molecular biology of the cell 25, 145-59. PMID: 24196833
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-FIS1 Polyclonal Antibody

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