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Anti-SUMF1 Polyclonal Antibody (ARO-A13720)

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概述
货号ARO-A13720
品牌ProteoGenix
描述
Anti-SUMF1 Polyclonal Antibody (ARO-A13720) is a rabbit polyclonal antibody detecting Formylglycine-generating enzyme, FGE, SUMF1, Sulfatase-modifying factor 1, C-alpha-formylglycine-generating enzyme 1 in ELISA, IHC, WB. Suitable for Bos taurus, Human, Mouse.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Bos taurus, Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human SUMF1 (Glu113-Ser356).
靶标Formylglycine-generating enzyme, FGE, SUMF1, Sulfatase-modifying factor 1, C-alpha-formylglycine-generating enzyme 1
纯化方式Purified by antigen affinity column.
Accession号Q8NBK3
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Formylglycine-generating enzyme (SUMF1) is a ~40 kDa protein. Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile. Known substrates include GALNS, ARSA, STS and ARSE.

1. Cosma, MP. et al. (2003) Cell 113, 445-56. PMID: 12757706
2. Preusser-Kunze, A. et al. (2005) The Journal of biological chemistry 280, 14900-10. PMID: 15657036
3. Dierks, T. et al. (2005) Cell 121, 541-552. PMID: 15907468
4. Roeser, D. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 81-6. PMID: 16368756
5. Schlotawa, L. et al. (2011) European journal of human genetics : EJHG 19, 253-61. PMID: 21224894
6. Holder, PG. et al. (2015) The Journal of biological chemistry 290, 15730-15745. PMID: 25931126
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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