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Anti-RALBP1 Polyclonal Antibody (ARO-A13793)

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概述
货号ARO-A13793
品牌ProteoGenix
描述
Anti-RALBP1 Polyclonal Antibody (ARO-A13793) is a rabbit polyclonal antibody detecting Dinitrophenyl S-glutathione ATPase, RLIP1, RalBP1, DNP-SG ATPase, 76 kDa Ral-interacting protein, Ral-interacting protein 1, RalA-binding protein 1, RLIP76, RALBP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Xenopus laevis.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat, Xenopus laevis
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human RALBP1 (Arg403-Met499).
靶标Dinitrophenyl S-glutathione ATPase, RLIP1, RalBP1, DNP-SG ATPase, 76 kDa Ral-interacting protein, Ral-interacting protein 1, RalA-binding protein 1, RLIP76, RALBP1
纯化方式Purified by antigen affinity column.
Accession号Q15311
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

RalA-binding protein 1 (RALBP1) is a ~76 kDa protein. Multifunctional protein that functions as a downstream effector of RALA and RALB. As a GTPase-activating protein/GAP can inactivate CDC42 and RAC1 by stimulating their GTPase activity. As part of the Ral signaling pathway, may also regulate ligand-dependent EGF and insulin receptors-mediated endocytosis. During mitosis, may act as a scaffold protein in the phosphorylation of EPSIN/EPN1 by the mitotic kinase cyclin B-CDK1, preventing endocytosis during that phase of the cell cycle. During mitosis, also controls mitochondrial fission as an effector of RALA.

1. Jullien-Flores, V. et al. (1995) The Journal of biological chemistry 270, 22473-7. PMID: 7673236
2. Jullien-Flores, V. et al. (2000) Journal of cell science 113 ( Pt 16), 2837-44. PMID: 10910768
3. Rossé, C. et al. (2003) The Journal of biological chemistry 278, 30597-604. PMID: 12775724
4. Kashatus, DF. et al. (2011) Nature cell biology 13, 1108-15. PMID: 21822277
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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