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Anti-CDC25B Polyclonal Antibody (ARO-A14014)

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概述
货号ARO-A14014
品牌ProteoGenix
描述
Anti-CDC25B Polyclonal Antibody (ARO-A14014) is a rabbit polyclonal antibody detecting Dual specificity phosphatase Cdc25B, CDC25B, CDC25HU2, M-phase inducer phosphatase 2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CDC25B (Cys377-Gly566).
靶标Dual specificity phosphatase Cdc25B, CDC25B, CDC25HU2, M-phase inducer phosphatase 2
纯化方式Purified by antigen affinity column.
Accession号P30305
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

M-phase inducer phosphatase 2 (CDC25B) is a ~64 kDa protein. Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. The three isoforms seem to have a different level of activity.

1. Galaktionov, K. et al. (1991) Cell 67, 1181-94. PMID: 1836978
2. Timofeev, O. et al. (2010) The Journal of biological chemistry 285, 16978-90. PMID: 20360007
3. Schmidt, A. et al. (2007) The EMBO journal 26, 1624-36. PMID: 17332740
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-CDC25B Polyclonal Antibody

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