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Anti-WT1 Polyclonal Antibody (ARO-A14079)

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概述
货号ARO-A14079
品牌ProteoGenix
描述
Anti-WT1 Polyclonal Antibody (ARO-A14079) is a rabbit polyclonal antibody detecting WT1, Wilms tumor protein, WT33 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Alligator mississippiensis, Sminthopsis macroura, Pig, Xenopus laevis, Xenopus tropicalis.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat, Alligator mississippiensis, Sminthopsis macroura, Pig, Xenopus laevis, Xenopus tropicalis
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human WT1 (Thr317-Gln446).
靶标WT1, Wilms tumor protein, WT33
纯化方式Purified by antigen affinity column.
Accession号P19544
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Wilms tumor protein (WT1) is a ~49 kDa protein. Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation.

1. Hamilton, TB. et al. (1995) Nucleic acids research 23, 277-84. PMID: 7862533
2. Stoll, R. et al. (2007) Journal of molecular biology 372, 1227-45. PMID: 17716689
3. Hashimoto, H. et al. (2014) Genes & development 28, 2304-13. PMID: 25258363
4. Smolen, GA. et al. (2004) Cancer research 64, 7846-51. PMID: 15520190
5. Markus, MA. et al. (2006) Experimental cell research 312, 3379-88. PMID: 16934801
6. Weiss, TC. et al. (2009) Biochemistry 48, 148-55. PMID: 19123921
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-WT1 Polyclonal Antibody

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