Anti-Yersinia pestis Plasminogen activator/Pla Polyclonal Antibody (JN173024)

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100ug

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概述
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参考文献
产品说明书

概述

货号

JN173024

品牌

abinScience

描述

Anti-Yersinia pestis Plasminogen activator/Pla Polyclonal Antibody (JN173024) is a rabbit polyclonal antibody detecting Plasminogen activator. Suitable for Yersinia pestis.

种属反应性

Yersinia pestis

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Yersinia pestis Plasminogen activator/Pla (Ala21-Phe312).

靶标

Coagulase/fibrinolysin, EC:3.4.23.48, Pla, Plasminogen activator, pla

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P17811

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Plasminogen activator is a ~34 kDa protein. In the mammalian host activates (cleaves) plasminogen to generate the serine protease plasmin. Plasmin degrades fibrin clots (fibrinolysis) and facilitates bacterial cell migration, enabling rapid dissemination of bacteria from the initial site of infection (Probable). Cleaves host plasminogen to generate plasmin and probably also has autocatalytic activity. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (28 degrees Celsius). Cleaves plasminogen; plasminogen cleavage is much higher than coagulase activity.

1. Eren, E. et al. (2010) Structure (London, England : 1993) 18, 809-18. PMID: 20637417

2. Eren, E. et al. (2012) The Journal of biological chemistry 287, 23971-6. PMID: 22645135

3. McDonough, KA. et al. (1989) Molecular microbiology 3, 767-75. PMID: 2526282

4. Sodeinde, OA. et al. (1989) Infection and immunity 57, 1517-23. PMID: 2651310

Note

For research use only

图片

参考文献

产品说明书

Anti-Yersinia pestis Plasminogen activator/Pla Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Yersinia pestis Plasminogen activator/Pla Polyclonal Antibody (JN173024)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Yersinia pestis Plasminogen activator/Pla Polyclonal Antibody (JN173024)

概述

图片

参考文献

产品说明书

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