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Anti-Human HCRTR2 Polyclonal Antibody (HD507014)

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规格:
  • 50ug
  • 100ug
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概述
货号HD507014
品牌abinScience
描述
Anti-Human HCRTR2 Polyclonal Antibody (HD507014) is a rabbit polyclonal antibody detecting HCRTR2. Suitable for Human.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human HCRTR2 (Ser2-Glu54&Glu192-Met222&Leu367-Trp444).
靶标HCRTR2, Hypocretin receptor type 2, ORXR2, OX2R, OXR2, Orexin receptor type 2, Ox-2-R, Ox2-R, Ox2R
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号O43614
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Orexin receptor type 2 (HCRTR2) is a ~50 kDa protein. G-protein coupled receptor that binds neuropeptides orexin-A and orexin-B, two neuropeptides derived from a common precursor, prepro-orexin. Upon neuropeptide ligand binding, HCRTR2 can couple with both G(q)/11 and G(i)/o heterotrimeric G-proteins thereby initiating distinct downstream signaling cascades. Involved in regulating the sleep-wake cycle. Contributes to central regulation of glucose homeostasis.

1. Yin, J. et al. (2016) Nature structural & molecular biology 23, 293-9. PMID: 26950369
2. Hong, C. et al. (2021) Nature communications 12, 815. PMID: 33547286
3. Yin, J. et al. (2022) Nature communications 13, 2902. PMID: 35614071
4. Sakurai, T. et al. (1998) Cell 92, 573-85. PMID: 9491897
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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