Anti-Human RPE65 Polyclonal Antibody (HD563014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HD563014

品牌

abinScience

描述

Anti-Human RPE65 Polyclonal Antibody (HD563014) is a rabbit polyclonal antibody detecting RPE65. Suitable for Mouse, Human, and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human RPE65 (Met1-Ser533).

靶标

All-trans-retinyl-palmitate hydrolase, EC:3.1.1.64, EC:5.3.3.22, Lutein isomerase, Meso-zeaxanthin isomerase, RPE65, Retinal pigment epithelium-specific 65 kDa protein, Retinoid isomerohydrolase, Retinol isomerase

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q16518

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Retinoid isomerohydrolase (RPE65) is a ~60 kDa protein. Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore. Essential for the production of 11-cis retinal for both rod and cone photoreceptors. Also capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester.

1. Moiseyev, G. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 12413-8. PMID: 16116091

2. Jacobson, SG. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 15123-8. PMID: 17848510

3. Shyam, R. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 10882-10887. PMID: 28874556

Note

For research use only

图片

参考文献

产品说明书

Anti-Human RPE65 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RPE65 Polyclonal Antibody (HD563014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RPE65 Polyclonal Antibody (HD563014)

概述

图片

参考文献

产品说明书

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