Anti-Human TMEM59 Polyclonal Antibody (HD403014)

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概述
图片
参考文献
产品说明书

概述

货号

HD403014

品牌

abinScience

描述

Anti-Human TMEM59 Polyclonal Antibody (HD403014) is a rabbit polyclonal antibody detecting TMEM59. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human TMEM59 (Gly45-Val135).

靶标

C1orf8, Liver membrane-bound protein, TMEM59, Transmembrane protein 59

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q9BXS4

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Transmembrane protein 59 (TMEM59) is a ~36 kDa protein. Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding.

1. Boada-Romero, E. et al. (2013) The EMBO journal 32, 566-82. PMID: 23376921

2. Boada-Romero, E. et al. (2016) Nature communications 7, 11821. PMID: 27273576

3. Ullrich, S. et al. (2010) The Journal of biological chemistry 285, 20664-74. PMID: 20427278

Note

For research use only

图片

参考文献

产品说明书

Anti-Human TMEM59 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TMEM59 Polyclonal Antibody (HD403014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TMEM59 Polyclonal Antibody (HD403014)

概述

图片

参考文献

产品说明书

相关产品推荐

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