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Human TMEM59 Recombinant Protein (N-GST & C-His) (HD403022)

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概述
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产品说明书

概述

货号	HD403022
品牌	abinScience
描述	Recombinant Human TMEM59 Protein, N-GST & C-His (HD403022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
表达系统	E. coli
Accession号	Q9BXS4
蛋白长度	Gly45-Val135
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	C1orf8, Liver membrane-bound protein, TMEM59, Transmembrane protein 59
背景	Transmembrane protein 59 is a ~36 kDa protein. Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding. 1. Boada-Romero, E. et al. (2013) The EMBO journal 32, 566-82. PMID: 23376921 2. Boada-Romero, E. et al. (2016) Nature communications 7, 11821. PMID: 27273576 3. Ullrich, S. et al. (2010) The Journal of biological chemistry 285, 20664-74. PMID: 20427278
Note	For research use only

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参考文献

产品说明书

Human TMEM59 Recombinant Protein (N-GST & C-His).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

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体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

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V₁ (起始体积)

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工作液

C₂ (终浓度)

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V₂ (终体积)

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Human TMEM59 Recombinant Protein (N-GST & C-His)

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