Anti-Human ITSN1 Polyclonal Antibody (HD585014)

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概述
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产品说明书

概述

货号

HD585014

品牌

abinScience

描述

Anti-Human ITSN1 Polyclonal Antibody (HD585014) is a rabbit polyclonal antibody detecting ITSN1. Suitable for Rat, Human, and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human ITSN1 (Asp1216-Leu1445).

靶标

ITSN, ITSN1, Intersectin-1, SH3 domain-containing protein 1A, SH3D1A, SH3P17

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q15811

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Intersectin-1 (ITSN1) is a ~195 kDa protein. Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as a guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex. Plays a role in the assembly and maturation of clathrin-coated vesicles. Recruits FCHSD2 to clathrin-coated pits. Involved in endocytosis of activated EGFR, and probably also other growth factor receptors.

1. Hussain, NK. et al. (2001) Nature cell biology 3, 927-32. PMID: 11584276

2. Almeida-Souza, L. et al. (2018) Cell 174, 325-337.e14. PMID: 29887380

3. Teckchandani, A. et al. (2012) Molecular biology of the cell 23, 2905-16. PMID: 22648170

4. Jenna, S. et al. (2002) The Journal of biological chemistry 277, 6366-73. PMID: 11744688

Note

For research use only

图片

参考文献

产品说明书

Anti-Human ITSN1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ITSN1 Polyclonal Antibody (HD585014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ITSN1 Polyclonal Antibody (HD585014)

概述

图片

参考文献

产品说明书

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