Anti-Human TMEFF1 Polyclonal Antibody (HP664014)

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概述
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产品说明书

概述

货号

HP664014

品牌

abinScience

描述

Anti-Human TMEFF1 Polyclonal Antibody (HP664014) is a rabbit polyclonal antibody detecting TMEFF1. Suitable for Mouse, Rat, and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human TMEFF1 (Gly86-Glu302).

靶标

C9orf2, H7365, TMEFF1, TR-1, Tomoregulin-1, Transmembrane protein with EGF-like and one follistatin-like domain

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q8IYR6

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Tomoregulin-1 (TMEFF1) is a ~40 kDa protein. Neuron-specific restriction factor that prevents herpes simplex virus 1 (HHV-1) infection in the brain by blocking viral entry. Also able to restrict herpes simplex virus 2 (HHV-2) infection, although to a lesser extent. Acts by preventing the association between the viral glycoprotein D (gD) and its cell surface receptor NECTIN1, thereby inhibiting fusion of the virus and the cell membrane. Also able to prevent the association between the viral glycoprotein B (gB) and MYH9/NMMHC-IIA and MYH10/NMMHC-IIB receptors. May be a tumor suppressor in brain cancers.

1. Dai, Y. et al. (2024) Nature 632, 383-389. PMID: 39048823

2. Chan, YH. et al. (2024) Nature 632, 390-400. PMID: 39048830

3. Gery, S. et al. (2003) Oncogene 22, 2723-7. PMID: 12743596

Note

For research use only

图片

参考文献

产品说明书

Anti-Human TMEFF1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TMEFF1 Polyclonal Antibody (HP664014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TMEFF1 Polyclonal Antibody (HP664014)

概述

图片

参考文献

产品说明书

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