Anti-MeV Non-structural protein V Polyclonal Antibody (VK815014)

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概述
图片
参考文献
产品说明书

概述

货号

VK815014

品牌

abinScience

描述

Anti-MeV Non-structural protein V Polyclonal Antibody (VK815014) is a rabbit polyclonal antibody detecting Non-structural protein V. Suitable for Measles virus.

种属反应性

Measles virus (MeV)

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant MeV Non-structural protein V (Met1-Gly231).

靶标

Non-structural protein V, P/V

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P0C774

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Non-structural protein V is a ~32 kDa protein. Plays an essential role in the inhibition of host immune response. Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway. Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state. Blocks the type I interferon signaling pathway by interacting with host TYK2 and thereby inhibiting downstream STAT1 and STAT2 phosphorylation. Blocks the type I interferon signaling pathway by disrupting the RIG-I signaling pathway.

1. Takeuchi, K. et al. (2003) FEBS letters 545, 177-82. PMID: 12804771

2. Parisien, JP. et al. (2009) Journal of virology 83, 7252-60. PMID: 19403670

3. Ramachandran, A. et al. (2008) Journal of virology 82, 8330-8. PMID: 18579593

4. Chinnakannan, SK. et al. (2013) PloS one 8, e57063. PMID: 23431397

5. Davis, ME. et al. (2014) Cell host & microbe 16, 19-30. PMID: 25011105

Note

For research use only

图片

参考文献

产品说明书

Anti-MeV Non-structural protein V Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-MeV Non-structural protein V Polyclonal Antibody (VK815014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-MeV Non-structural protein V Polyclonal Antibody (VK815014)

概述

图片

参考文献

产品说明书

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