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MeV Non-structural V Recombinant Protein (N-His) (VK815012)

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概述
货号VK815012
品牌abinScience
描述
Recombinant MeV Non-structural protein V, N-His (VK815012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
表达系统E. coli
Accession号P0C774
蛋白长度Met1-Gly231
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Measles virus (MeV)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Non-structural protein V, P/V
背景

Non-structural protein V is a ~32 kDa protein. Plays an essential role in the inhibition of host immune response. Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway. Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state. Blocks the type I interferon signaling pathway by interacting with host TYK2 and thereby inhibiting downstream STAT1 and STAT2 phosphorylation. Blocks the type I interferon signaling pathway by disrupting the RIG-I signaling pathway.

1. Takeuchi, K. et al. (2003) FEBS letters 545, 177-82. PMID: 12804771
2. Parisien, JP. et al. (2009) Journal of virology 83, 7252-60. PMID: 19403670
3. Ramachandran, A. et al. (2008) Journal of virology 82, 8330-8. PMID: 18579593
4. Chinnakannan, SK. et al. (2013) PloS one 8, e57063. PMID: 23431397
5. Davis, ME. et al. (2014) Cell host & microbe 16, 19-30. PMID: 25011105
NoteFor research use only
图片

  • SDS-PAGE

    SDS-PAGE for Recombinant MeV V/Non-structural protein V Protein, N-His

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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MeV Non-structural V Recombinant Protein (N-His)

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