首页 > 产品中心 > 抗体 > 一抗

Anti-Mouse CD365/KIM-1/TIM-1/HAVCR1 Polyclonal Antibody (MV277014)

价格:
规格:
  • 50ug
  • 100ug
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号MV277014
品牌abinScience
描述
Anti-Mouse CD365/KIM-1/TIM-1/HAVCR1 Polyclonal Antibody (MV277014) is a rabbit polyclonal antibody detecting HAVCR1. Suitable for Mouse.
种属反应性Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Mouse CD365/KIM-1/TIM-1/HAVCR1 (Tyr22-Gly237).
靶标CD365, HAVCR1, HAVcr-1, Hepatitis A virus cellular receptor 1, KIM-1, KIM1, Kidney injury molecule 1, T-cell immunoglobulin and mucin domain-containing protein 1, T-cell immunoglobulin mucin receptor 1, T-cell membrane protein 1, TIM, TIM-1, TIM1, TIMD-1, TIMD1
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q5QNS5
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Hepatitis A virus cellular receptor 1 homolog (CD365/KIM-1) is a ~33 kDa protein. Phosphatidylserine receptor that plays an important functional role in regulatory B-cell homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Also regulates expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as a regulator of T-cell proliferation.

1. Ding, Q. et al. (2011) The Journal of clinical investigation 121, 3645-56. PMID: 21821911
2. Yeung, MY. et al. (2015) American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 15, 942-53. PMID: 25645598
3. Xiao, S. et al. (2020) Cell reports 32, 107892. PMID: 32668241
4. Angiari, S. et al. (2014) Immunity 40, 542-53. PMID: 24703780
5. Xiao, S. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 1602-8. PMID: 25582854
6. Meyers, JH. et al. (2005) Nature immunology 6, 455-64. PMID: 15793576
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐