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Anti-Human TSPAN14 Polyclonal Antibody (HD404014)

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概述
货号HD404014
品牌abinScience
描述
Anti-Human TSPAN14 Polyclonal Antibody (HD404014) is a rabbit polyclonal antibody detecting TSPAN14. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human TSPAN14 (Leu114-Asn232).
靶标DC-TM4F2, TM4SF14, TSPAN14, Tetraspanin-14, Transmembrane 4 superfamily member 14, Tspan-14
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q8NG11
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Tetraspanin-14 (TSPAN14) is a ~30 kDa protein. Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Negatively regulates ADAM10-mediated cleavage of GP6. Promotes ADAM10-mediated cleavage of CDH5.

1. Haining, EJ. et al. (2012) The Journal of biological chemistry 287, 39753-65. PMID: 23035126
2. Noy, PJ. et al. (2016) The Journal of biological chemistry 291, 3145-57. PMID: 26668317
3. Jouannet, S. et al. (2016) Cellular and molecular life sciences : CMLS 73, 1895-915. PMID: 26686862
4. Lipper, CH. et al. (2023) Cell 186, 3632-3641.e10. PMID: 37516108
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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