

| 货号 | HD404012 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human TSPAN14 Protein, N-His (HD404012) expressed in E. coli, spanning Leu114-Asn232. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q8NG11 |
| 蛋白长度 | Leu114-Asn232 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 16.12 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | DC-TM4F2, TM4SF14, TSPAN14, Tetraspanin-14, Transmembrane 4 superfamily member 14, Tspan-14 |
| 背景 | Tetraspanin-14 is a ~30 kDa protein. Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Negatively regulates ADAM10-mediated cleavage of GP6. Promotes ADAM10-mediated cleavage of CDH5. 1. Haining, EJ. et al. (2012) The Journal of biological chemistry 287, 39753-65. PMID: 23035126 2. Noy, PJ. et al. (2016) The Journal of biological chemistry 291, 3145-57. PMID: 26668317 3. Jouannet, S. et al. (2016) Cellular and molecular life sciences : CMLS 73, 1895-915. PMID: 26686862 4. Lipper, CH. et al. (2023) Cell 186, 3632-3641.e10. PMID: 37516108 |
| Note | For research use only |

24小时产品查询

扫一扫关注我们

专属渠道经理