

| 货号 | HD356014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human ENPP7 Polyclonal Antibody (HD356014) is a rabbit polyclonal antibody detecting ENPP7. Suitable for Human.
| ||||||||
| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ENPP7 (Asn31-Leu413). | ||||||||
| 靶标 | Alk-SMase, Alkaline sphingomyelin phosphodiesterase, E-NPP 7, EC:3.1.4.12, ENPP7, Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, Intestinal alkaline sphingomyelinase, NPP-7 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q6UWV6 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 背景 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (ENPP7) is a ~51 kDa protein. Choline-specific phosphodiesterase that hydrolyzes sphingomyelin releasing the ceramide and phosphocholine and therefore is involved in sphingomyelin digestion, ceramide formation, and fatty acid (FA) absorption in the gastrointestinal tract. Also has phospholipase C activity and can also cleave phosphocholine from palmitoyl lyso-phosphatidylcholine and platelet-activating factor (PAF) leading to its inactivation. Does not have nucleotide pyrophosphatase activity. May promote cholesterol absorption by affecting the levels of sphingomyelin derived from either diet or endogenous sources, in the intestinal lumen. 1. Duan, RD. et al. (2003) Journal of lipid research 44, 1241-50. PMID: 12671034 2. Duan, RD. et al. (2003) The Journal of biological chemistry 278, 38528-36. PMID: 12885774 3. Wu, J. et al. (2004) American journal of physiology. Gastrointestinal and liver physiology 287, G967-73. PMID: 15205117 4. Wu, J. et al. (2006) The Biochemical journal 394, 299-308. PMID: 16255717 5. Gorelik, A. et al. (2017) The Journal of biological chemistry 292, 7087-7094. PMID: 28292932 | ||||||||
| Note | For research use only |

24小时产品查询

扫一扫关注我们

专属渠道经理