Anti-Human LUZP1 Polyclonal Antibody (HC252014)

价格:

规格：

50ug
100ug

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

HC252014

品牌

abinScience

描述

Anti-Human LUZP1 Polyclonal Antibody (HC252014) is a rabbit polyclonal antibody detecting LUZP1. Suitable for Human and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human LUZP1 (Met157-Gln350).

靶标

Filamin mechanobinding actin cross-linking protein, Fimbacin, LUZP1, Leucine zipper protein 1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q86V48

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Leucine zipper protein 1 (LUZP1) is a ~120 kDa protein. F-actin cross-linking protein. Stabilizes actin and acts as a negative regulator of primary cilium formation. Positively regulates the phosphorylation of both myosin II and protein phosphatase 1 regulatory subunit PPP1R12A/MYPT1 and promotes the assembly of myosin II stacks within actin stress fibers. Inhibits the phosphorylation of myosin light chain MYL9 by DAPK3 and suppresses the constriction velocity of the contractile ring during cytokinesis. Binds to microtubules and promotes epithelial cell apical constriction by up-regulating levels of diphosphorylated myosin light chain (MLC) through microtubule-dependent inhibition of MLC dephosphorylation by myosin phosphatase.

1. Wang, J. et al. (2019) Biochemistry 58, 4737-4743. PMID: 30990684

2. Gonçalves, J. et al. (2020) The Journal of cell biology 219. PMID: 32496561

3. Wang, L. et al. (2024) Cellular and molecular life sciences : CMLS 81, 248. PMID: 38832964

4. Hyodo, T. et al. (2024) The FEBS journal 291, 927-944. PMID: 38009294

Note

For research use only

图片

参考文献

产品说明书

Anti-Human LUZP1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LUZP1 Polyclonal Antibody (HC252014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LUZP1 Polyclonal Antibody (HC252014)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价