Human LUZP1 Recombinant Protein (N-His) (HC252012)

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概述

货号	HC252012
品牌	abinScience
描述	Recombinant Human LUZP1 Protein, N-His (HC252012) expressed in E. coli, spanning Met157-Gln350. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
表达系统	E. coli
Accession号	Q86V48
蛋白长度	Met157-Gln350
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	25.22 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	Filamin mechanobinding actin cross-linking protein, Fimbacin, LUZP1, Leucine zipper protein 1
背景	Leucine zipper protein 1 is a ~120 kDa protein. F-actin cross-linking protein. Stabilizes actin and acts as a negative regulator of primary cilium formation. Positively regulates the phosphorylation of both myosin II and protein phosphatase 1 regulatory subunit PPP1R12A/MYPT1 and promotes the assembly of myosin II stacks within actin stress fibers. Inhibits the phosphorylation of myosin light chain MYL9 by DAPK3 and suppresses the constriction velocity of the contractile ring during cytokinesis. Binds to microtubules and promotes epithelial cell apical constriction by up-regulating levels of diphosphorylated myosin light chain (MLC) through microtubule-dependent inhibition of MLC dephosphorylation by myosin phosphatase. 1. Wang, J. et al. (2019) Biochemistry 58, 4737-4743. PMID: 30990684 2. Gonçalves, J. et al. (2020) The Journal of cell biology 219. PMID: 32496561 3. Wang, L. et al. (2024) Cellular and molecular life sciences : CMLS 81, 248. PMID: 38832964 4. Hyodo, T. et al. (2024) The FEBS journal 291, 927-944. PMID: 38009294
Note	For research use only

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参考文献

产品说明书

Human LUZP1 Recombinant Protein (N-His).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Human LUZP1 Recombinant Protein (N-His) (HC252012)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Human LUZP1 Recombinant Protein (N-His) (HC252012)

概述

图片

参考文献

产品说明书

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