

| 货号 | HC205014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human DDX17 Polyclonal Antibody (HC205014) is a rabbit polyclonal antibody detecting DDX17. Suitable for Human and Mouse.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human DDX17 (Glu137-Gly556). | ||||||||
| 靶标 | DDX17, DEAD box protein 17, DEAD box protein p72, DEAD box protein p82, EC:3.6.4.13, Probable ATP-dependent RNA helicase DDX17, RNA-dependent helicase p72 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q92841 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 背景 | Probable ATP-dependent RNA helicase DDX17 is a ~80 kDa protein. As an RNA helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. Involved in multiple cellular processes, including pre-mRNA splicing, alternative splicing, ribosomal RNA processing and miRNA processing, as well as transcription regulation. Regulates the alternative splicing of exons exhibiting specific features. For instance, promotes the inclusion of AC-rich alternative exons in CD44 transcripts. This function requires the RNA helicase activity. 1. Hönig, A. et al. (2002) Molecular and cellular biology 22, 5698-707. PMID: 12138182 2. Germann, S. et al. (2012) Oncogene 31, 4536-49. PMID: 22266867 3. Dardenne, E. et al. (2012) Nature structural & molecular biology 19, 1139-46. PMID: 23022728 4. Dardenne, E. et al. (2014) Cell reports 7, 1900-13. PMID: 24910439 | ||||||||
| Note | For research use only |

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