Human DDX17 Recombinant Protein (C-Strep) (HC205011)
概述
图片
参考文献
产品说明书
概述
货号
HC205011
品牌
abinScience
描述
Recombinant Human DDX17 Protein, C-Strep (HC205011) expressed in Insect Cells, spanning Gly111-Gly556. Purity: >90% by SDS-PAGE.
Highlights
●High Purity — >90% purity verified by SDS-PAGE.
表达系统
Insect cells
Accession号
Q92841
蛋白长度
Gly111-Gly556
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
52.39 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
DDX17, DEAD box protein 17, DEAD box protein p72, DEAD box protein p82, EC:3.6.4.13, Probable ATP-dependent RNA helicase DDX17, RNA-dependent helicase p72
背景
Probable ATP-dependent RNA helicase DDX17 is a ~80 kDa protein. As an RNA helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. Involved in multiple cellular processes, including pre-mRNA splicing, alternative splicing, ribosomal RNA processing and miRNA processing, as well as transcription regulation. Regulates the alternative splicing of exons exhibiting specific features. For instance, promotes the inclusion of AC-rich alternative exons in CD44 transcripts. This function requires the RNA helicase activity.
1. Hönig, A. et al. (2002) Molecular and cellular biology 22, 5698-707. PMID: 12138182
2. Germann, S. et al. (2012) Oncogene 31, 4536-49. PMID: 22266867
3. Dardenne, E. et al. (2012) Nature structural & molecular biology 19, 1139-46. PMID: 23022728
4. Dardenne, E. et al. (2014) Cell reports 7, 1900-13. PMID: 24910439
