Anti-Human KAT2B Polyclonal Antibody (HA390024)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HA390024

品牌

abinScience

描述

Anti-Human KAT2B Polyclonal Antibody (HA390024) is a rabbit polyclonal antibody detecting KAT2B. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human KAT2B (Asn651-Lys818).

靶标

EC:2.3.1.48, EC:2.3.1.57, Histone acetylase PCAF, Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, KAT2B, Lysine acetyltransferase 2B, P/CAF, P300/CBP-associated factor, PCAF, Spermidine acetyltransferase KAT2B

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q92831

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Histone acetyltransferase KAT2B is a ~93 kDa protein. Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Has a a strong preference for acetylation of H3 at 'Lys-9' (H3K9ac). Also acetylates non-histone proteins, such as ACLY, MAPRE1/EB1, PLK4, RRP9/U3-55K and TBX5. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A.

1. Ogryzko, VV. et al. (1996) Cell 87, 953-9. PMID: 8945521

2. Jin, Q. et al. (2011) The EMBO journal 30, 249-62. PMID: 21131905

3. Martínez-Balbás, MA. et al. (2000) The EMBO journal 19, 662-71. PMID: 10675335

4. Xia, P. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 16564-9. PMID: 23001180

5. Lin, R. et al. (2013) Molecular cell 51, 506-518. PMID: 23932781

6. Chen, S. et al. (2016) Nature communications 7, 10734. PMID: 26867678

7. Fournier, M. et al. (2016) Nature communications 7, 13227. PMID: 27796307

8. Ghosh, TK. et al. (2018) Journal of molecular and cellular cardiology 114, 185-198. PMID: 29174768

9. Zhang, W. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 9855-60. PMID: 9707565

Note

For research use only

图片

参考文献

产品说明书

Anti-Human KAT2B Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KAT2B Polyclonal Antibody (HA390024)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KAT2B Polyclonal Antibody (HA390024)

概述

图片

参考文献

产品说明书

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