Anti-Phospho-Tau Tau (pT217) Recombinant Antibody (SAA2786) (HY086263)

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货号	HY086263
品牌	abinScience
种属反应性	Human
应用	ELISA, DB, IF
宿主	Rabbit
克隆类型	Monoclonal
同种型	IgG
克隆号	SAA2786
靶标	MAPT, MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau, TAU
内毒素水平	< 10 EU/mg
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P10636
状态	Liquid
保存溶液	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Microtubule-associated protein tau (Tau pT217) is a ~78 kDa protein. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. 1. Yoshida, H. et al. (2012) Journal of neurochemistry 120, 165-76. PMID: 21985311 2. Sandberg, A. et al. (2020) Neurobiology of disease 146, 105079. PMID: 32961270
Note	For research use only

产品说明书

Anti-Phospho-Tau Tau (pT217) Recombinant Antibody (SAA2786).pdf

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Anti-Phospho-Tau Tau (pT217) Recombinant Antibody (SAA2786) (HY086263)

概述

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参考文献

产品说明书

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重组蛋白

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试剂盒

实验相关试剂

Anti-Phospho-Tau Tau (pT217) Recombinant Antibody (SAA2786) (HY086263)

概述

图片

参考文献

产品说明书

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