Anti-ABCA1 Polyclonal Antibody (HF602014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HF602014

品牌

abinScience

描述

Anti-ABCA1 Polyclonal Antibody (HF602014) is a rabbit polyclonal antibody detecting ABCA1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human ABCA1 (Ser45-Glu271).

靶标

ATP-binding cassette transporter 1, ATP-binding cassette sub-family A member 1, Phospholipid-transporting ATPase ABCA1, ABC-1, ABCA1, ATP-binding cassette 1, Cholesterol efflux regulatory protein, ABC1, CERP

纯化方式

Purified by antigen affinity column.

Accession号

O95477

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Phospholipid-transporting ATPase ABCA1 is a ~254 kDa protein. Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP. Thereby, participates in phospholipid transfer to apolipoproteins to form nascent high density lipoproteins/HDLs. Transports preferentially phosphatidylcholine over phosphatidylserine. May play a similar role in the efflux of intracellular cholesterol to apolipoproteins and the formation of nascent high density lipoproteins/HDLs. Translocates phospholipids from the outer face of the plasma membrane and forces it through its gateway and annulus into an elongated hydrophobic tunnel in its extracellular domain.

1. Quazi, F. et al. (2013) The Journal of biological chemistry 288, 34414-26. PMID: 24097981

2. Segrest, JP. et al. (2022) Nature communications 13, 4812. PMID: 35974019

3. Krimbou, L. et al. (2004) Journal of lipid research 45, 839-48. PMID: 14754908

4. Marcil, M. et al. (1999) Lancet (London, England) 354, 1341-6. PMID: 10533863

Note

For research use only.

图片

参考文献

产品说明书

Anti-ABCA1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ABCA1 Polyclonal Antibody (HF602014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ABCA1 Polyclonal Antibody (HF602014)

概述

图片

参考文献

产品说明书

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