Anti-STAMBP Polyclonal Antibody (HF596014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HF596014

品牌

abinScience

描述

Anti-STAMBP Polyclonal Antibody (HF596014) is a rabbit polyclonal antibody detecting STAMBP in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human STAMBP (Lys126-Ser368).

靶标

Endosome-associated ubiquitin isopeptidase, STAM-binding protein, AMSH, Associated molecule with the SH3 domain of STAM, STAMBP

纯化方式

Purified by antigen affinity column.

Accession号

O95630

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

STAM-binding protein (STAMBP) is a ~48 kDa protein. Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes.

1. McCullough, J. et al. (2004) The Journal of cell biology 166, 487-92. PMID: 15314065

2. McDonell, LM. et al. (2013) Nature genetics 45, 556-62. PMID: 23542699

3. Guo, Y. et al. (2021) The Journal of biological chemistry 297, 101107. PMID: 34425109

4. Tanaka, N. et al. (1999) The Journal of biological chemistry 274, 19129-35. PMID: 10383417

5. Itoh, F. et al. (2001) The EMBO journal 20, 4132-42. PMID: 11483516

6. Ma, YM. et al. (2007) The Journal of biological chemistry 282, 9805-9812. PMID: 17261583

Note

For research use only.

图片

参考文献

产品说明书

Anti-STAMBP Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-STAMBP Polyclonal Antibody (HF596014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-STAMBP Polyclonal Antibody (HF596014)

概述

图片

参考文献

产品说明书

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