Anti-PTBP1 Polyclonal Antibody (HB835014)

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概述
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产品说明书

概述

货号

HB835014

品牌

abinScience

描述

Anti-PTBP1 Polyclonal Antibody (HB835014) is a rabbit polyclonal antibody detecting PTBP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Rat, and Pig.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Human PTBP1 (Met1-Ile531).

靶标

PTB, Polypyrimidine tract-binding protein 1, 57 kDa RNA-binding protein PPTB-1, PTBP1, Heterogeneous nuclear ribonucleoprotein I, hnRNP I

纯化方式

Purified by antigen affinity column.

Accession号

P26599

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Polypyrimidine tract-binding protein 1 (PTBP1) is a ~59 kDa protein. Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA.

1. Wang, J. et al. (2004) Journal of neurochemistry 88, 1078-90. PMID: 15009664

2. Zuccato, E. et al. (2004) The Journal of biological chemistry 279, 16980-8. PMID: 14966131

3. David, CJ. et al. (2010) Nature 463, 364-8. PMID: 20010808

4. Kafasla, P. et al. (2011) RNA (New York, N.Y.) 17, 1120-31. PMID: 21518806

Note

For research use only.

图片

参考文献

产品说明书

Anti-PTBP1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PTBP1 Polyclonal Antibody (HB835014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PTBP1 Polyclonal Antibody (HB835014)

概述

图片

参考文献

产品说明书

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